Figured I’d write this up while it’s fresh.
Went through the Institute reports on this and it’s genuinely useful, but I only understand maybe 60% of what I’m looking at.
The thing nobody tells you is that the certificate is about one batch. Not the product. One batch.
For what it’s worth the Institute has 1 published Vilon report, which is where I started.
Anyway. Curious what everyone else has seen.
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I stopped chasing the new compounds a while back. The interesting stuff is boring and the exciting stuff is usually unsupported.
Batch-to-batch variation is the thing people underestimate. A passing result certifies one lot, not a product line, and vendors know most buyers do not make that distinction.
Mass spec gives you molecular weight, which confirms identity but says nothing about whether the sequence is correct. Two different peptides can share a mass.
Thanks.
DE DevReview ·
What would actually change your mind here? If nothing would, it is not really an evidence question.