Research
Retatrutide phase 3 data shows sustained metabolic improvements at 68 weeks
Interim results from the TRIUMPH program suggest the triple agonist maintains its lead over dual-incretin therapy on weight and liver-fat endpoints.
Study summaries, mechanism reviews, and scientific analysis — written in plain English and graded against a transparent evidence taxonomy.
Research
Interim results from the TRIUMPH program suggest the triple agonist maintains its lead over dual-incretin therapy on weight and liver-fat endpoints.
Angiogenesis modulation, growth-factor signaling, and the gaps between rodent data and human claims.
ScienceSURMOUNT-5 and real-world cohorts consistently favor the dual agonist on weight endpoints — with nuances the headlines skip.
ResearchStrong topical literature, thin injectable data — a compound with a genuinely split evidence base.
SciencePhase 3 readouts, new obesity candidates, and the muscle-preservation programs entering the clinic.
Clinical TrialsThe synergy claim has real pharmacology behind it — and important measurement caveats.
SciencePeptides encoded in mitochondrial DNA are rewriting assumptions about the genome’s smallest products.
ScienceDecades of source-country research, near-zero independent replication: how to weigh geographically concentrated evidence.
ScienceA full FDA approval, phase 3 visceral-fat data, and lessons for evaluating its gray-market cousins.
ScienceApproved in one country, unstudied in most others — a framework for reading asymmetric evidence.
ScienceThe obesity program failed in 2007. The marketing never stopped. A case study in zombie evidence.
ScienceThe Peptide Institute Weekly
One email a week: new study summaries, the latest independent lab results, ranking movements, and regulatory developments that matter.