Science

Epitalon and the replication problem in longevity peptides

Decades of source-country research, near-zero independent replication: how to weigh geographically concentrated evidence.

Epitalon presents an evidence-evaluation puzzle: a large body of research from a single institutional lineage, with striking claims about telomerase and lifespan, and almost no independent replication attempts in Western literature.

This is not automatically disqualifying — but unreplicated geographically concentrated evidence warrants the Limited grade in our evidence taxonomy, and readers should understand why the distinction matters more here than citation counts.

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