Epitalon and the replication problem in longevity peptides
Decades of source-country research, near-zero independent replication: how to weigh geographically concentrated evidence.
ScienceEpitalon
Also known as: Epithalon, AEDG peptide
ClassSynthetic pineal tetrapeptide
Research statusPreclinical / limited foreign trials
Independent tests0
Studies indexed1
Overview
Epitalon is a four-amino-acid synthetic peptide developed in Russian gerontology research, where studies reported effects on telomerase activity and lifespan in animal models. Independent Western replication of these findings is essentially absent, which is why we classify its evidence level as Limited despite decades of use in the source literature.
Research & Studies
Studies library-
Epithalon and telomerase activity in human somatic cells
Reported telomerase activation in vitro; central to the compound’s longevity claims and largely unreplicated independently.
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