Peptide Directory

Permanent research reference pages for every compound we track. Each page grades the evidence, summarizes the research landscape, and connects testing data, reporting, and community discussion. Educational reference only — not medical advice.

Evidence levels: Strong Moderate Emerging Limited
PT-141 Melanocortin receptor agonist
Strong

A melanocortin agonist approved as Vyleesi for hypoactive sexual desire disorder in premenopausal women.

FDA-approved (branded form) 1 test 1 article
Semaglutide GLP-1 receptor agonist
Strong

A long-acting GLP-1 receptor agonist approved for type 2 diabetes and chronic weight management, supported by large randomized controlled trials.

FDA-approved (branded forms) 3 tests 8 articles
Tesamorelin GHRH analog
Strong

A stabilized GHRH analog approved for HIV-associated lipodystrophy, with visceral-fat reduction demonstrated in phase 3 trials.

FDA-approved (branded form) 1 article
Tirzepatide Dual GIP/GLP-1 receptor agonist
Strong

A dual-incretin agonist targeting both GIP and GLP-1 receptors, with weight-reduction results exceeding single-agonist therapies in head-to-head trials.

FDA-approved (branded forms) 2 tests 6 articles
GHK-Cu Naturally occurring copper-binding tripeptide
Moderate

A copper-binding tripeptide found in human plasma, extensively studied in skin-repair and cosmetic contexts.

Cosmetic use / preclinical 2 tests 1 article
Retatrutide Triple GIP/GLP-1/glucagon receptor agonist
Moderate

An investigational triple-agonist in late-stage trials, with phase 2 data showing the largest weight reductions yet reported for an incretin therapy.

Phase 3 clinical trials 2 tests 2 articles
BPC-157 Synthetic gastric pentadecapeptide
Emerging

A 15-amino-acid fragment derived from a protective protein in gastric juice, studied primarily in animal models of tendon, ligament, muscle, and gastrointestinal injury.

Preclinical / early human studies 6 tests 6 articles
CJC-1295 Growth-hormone-releasing hormone analog
Emerging

A GHRH analog engineered for extended half-life, studied for its ability to raise growth hormone and IGF-1 levels.

Preclinical / early human studies 2 tests 3 articles
Ipamorelin Ghrelin receptor agonist (GH secretagogue)
Emerging

A selective growth-hormone secretagogue studied for GH release with minimal effect on cortisol and prolactin.

Discontinued clinical development 2 tests 1 article
MOTS-c Mitochondrial-derived peptide
Emerging

A mitochondrial-encoded peptide studied in metabolism and exercise-physiology research.

Preclinical / early human trials 1 test 2 articles
TB-500 Synthetic thymosin beta-4 derivative
Emerging

A synthetic version of a naturally occurring actin-binding peptide studied in models of tissue repair, cell migration, and cardiac injury.

Preclinical 3 tests 2 articles
AOD-9604 hGH C-terminal fragment
Limited

A growth-hormone fragment studied for fat metabolism; failed to meet endpoints in obesity trials.

Discontinued clinical development 1 article
Epitalon Synthetic pineal tetrapeptide
Limited

A tetrapeptide studied primarily in Russian longevity research; Western replication remains minimal.

Preclinical / limited foreign trials 1 article
Selank Synthetic tuftsin analog
Limited

An anxiolytic heptapeptide approved in Russia as a nasal spray; minimal Western clinical data.

Approved in Russia; unapproved elsewhere 1 article
Semax Synthetic ACTH(4-10) analog
Limited

A nootropic-classified heptapeptide used clinically in Russia for stroke and cognitive indications.

Approved in Russia; unapproved elsewhere 2 articles