Setmelanotide

An MC4R agonist approved for rare genetic obesity syndromes, with a narrow and well-defined indication.

Setmelanotide is classified as a mc4r agonist. Its current development status is: fda-approved (branded form). Multiple randomised controlled trials in humans support the primary claims made for this compound.

The Peptide Institute tracks Setmelanotide because it is actively sold through research-compound and telehealth channels. Our interest is narrow and specific: what is actually in the vial, whether the label is accurate, and whether the sellers of it can document what they claim. We take no position on whether anyone should use it.