TB-500

Also known as: Thymosin Beta-4 fragment, TB4

Emerging evidence
ClassSynthetic thymosin beta-4 derivative
Research statusPreclinical
Independent tests3
Studies indexed2

Overview

TB-500 refers to synthetic thymosin beta-4 or its active fragment. Thymosin beta-4 is a naturally occurring 43-amino-acid peptide that regulates actin polymerization, a process central to cell movement and tissue repair.

Preclinical research has examined wound healing, corneal repair, and cardiac tissue models. As with most research peptides, human data is sparse, and product quality varies between suppliers — TB-500 has produced both our highest and most variable purity results in independent testing.

Research & Studies

Studies library

  • Thymosin beta-4 ophthalmic solution for dry eye (phase 3 program)

    Clinical trial registry record · Randomized controlled trial (Phase 3) · Sep 1, 2020

    The furthest-advanced human application of TB4 biology; results mixed across endpoints.

  • Thymosin beta-4 promotes cardiomyocyte survival after coronary ligation

    Nature · Animal model · Nov 25, 2004

    Landmark cardiac-repair finding that anchored interest in thymosin beta-4 biology.

Independent Testing

Testing database

Laboratory verification of TB-500 products across the companies we index.

TB-500 BioRegen Research
Purity 99.2% Verified
TB-500 Meridian Peptide Research
Purity 98.6% Verified
TB-500 Sterling Compound Co.
Purity 98.5% Verified

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