BPC-157 oral vs. injectable bioavailability — what does the literature say?

Started by SkepticalSam · · 38 replies · 4,110 views

Member since Dec 1, 2025 · 76 posts

Capsule products are everywhere now. Is there any direct evidence the peptide survives the GI tract, or is the gastric-stability claim doing all the work?

Replies — showing 2 of 38

141 posts

The honest answer: the compound was literally derived from a gastric protein and shows activity in oral rodent GI models. Systemic oral bioavailability in humans is unmeasured. Anyone quoting a percentage is inventing it.

44 found helpful

176 posts

Note the rodent oral studies used doses that scale to far more than typical capsule products contain. The stability claim and the dose reality are different problems.

30 found helpful

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