Regulation

Compounding rules tighten around TB-500

Purity across our TB-500 samples ranged from 97.4% to 99.7%. Here is the context.

Compounding rules tighten around TB-500

TB-500 is a synthetic thymosin beta-4 derivative with a development status of "preclinical". The Institute rates the strength of its published evidence as emerging. A synthetic version of a naturally occurring actin-binding peptide studied in models of tissue repair, cell migration, and cardiac injury.

Commercial availability of TB-500 continues to run ahead of its regulatory status. That is the recurring structural feature of this market: demand arrives when trial data is published, and supply arrives from channels that answer to nobody in particular.

Our position on developments like this is consistent. We report what changed, we test what is being sold, and we decline to speculate about what a regulator will do next.

The Institute has independently tested 7 TB-500 samples from 6 companies. 100% met their label claims on purity and content. Measured purity ranged from 97.4% to 99.7%, averaging 98.3%. Every specimen is published in full, including the laboratory that ran it.

The Peptide Institute is an independent research institute. We do not sell products, we do not accept vendor sponsorship, and we publish results that reflect badly on companies as readily as results that do not.

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